Insights in Gynecologic Oncology
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James P. Patel
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Role of PARP Inhibitors in Ovarian Cancer
Ovarian cancer, a leading cause of gynecologic cancer mortality, is characterized by DNA repair deficiencies in up to 50% of cases, particularly in BRCA-mutated and homologous recombination-deficient (HRD) tumors. Poly (ADPribose) polymerase (PARP) inhibitors, such as olaparib, niraparib, and rucaparib, exploit these vulnerabilities, offering signi... Read More»
: Current Trends Gynecol Oncol 2025, 10:260
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