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Journal of Oral Hygiene & Health
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  • Opinion Article   
  • J Oral Hyg Health, Vol 13(6)

Modern Endodontics: Advancements, Diagnostics, Regeneration, Challenges

James O芒聙聶Neil*
Dept. of Preventive Dentistry, Dublin Dental College, University College Dublin, Dublin, Ireland
*Corresponding Author: James O芒聙聶Neil, Dept. of Preventive Dentistry, Dublin Dental College, University College Dublin, Dublin, Ireland, Email: j.oneil@ddcucd.ie

Received: 01-Nov-2025 / Manuscript No. johh-25-174157 / Editor assigned: 03-Nov-2025 / PreQC No. johh-25-174157 (PQ) / Reviewed: 17-Nov-2025 / QC No. johh-25-174157 / Revised: 24-Nov-2025 / Manuscript No. johh-25-174157 (R) / Published Date: 01-Dec-2025

Abstract

This compilation of systematic reviews and meta-analyses highlights critical advancements and ongoing challenges in endodontics. It covers improved irrigation techniques for smear layer and biofilm disruption, the development of biocompatible root canal sealers, and the success of regenerative procedures for immature teeth. Diagnostic precision is enhanced by Cone-beam Computed Tomography (CBCT), revealing higher prevalence of apical periodontitis than traditional radiography. Challenges remain in complete smear layer removal, retreatment efficacy, and individualized pain management, underscoring the continuous evolution of materials, techniques, and diagnostic tools for optimal patient outcomes.

Keywords

Root Canal Treatment; Endodontics; Irrigation Techniques; Smear Layer; Biofilm Disruption; Pain Management; Regenerative Endodontics; CBCT; Apical Periodontitis; Retreatment

Introduction

Current endodontic practices strive for thorough disinfection and successful long-term outcomes, often facing persistent challenges. Researchers continue to explore ways to improve root canal treatment, from enhancing cleaning protocols to refining diagnostic methods. For example, while various irrigation techniques improve smear layer removal in root canals, none consistently achieve complete elimination, with passive ultrasonic irrigation and laser-activated irrigation showing promise in enhancing cleanliness compared to conventional needle irrigation [1].

Further advancing disinfection efforts, systematic reviews exploring methods to disrupt tenacious bacterial biofilms indicate that adjunctive activation methods significantly enhance biofilm disruption when combined with conventional irrigants. This highlights the ongoing need to move beyond simple irrigation for optimal disinfection, particularly in complex root canal anatomies [2].

Patient comfort remains a priority, and research into the role of local anesthetics in managing pain during and after root canal treatment reveals that while they are generally effective, a notable percentage of patients still experience some degree of pain, especially post-operatively. This finding emphasizes the need for individualized pain management strategies and potentially adjunct therapies [3].

The materials used in root canal obturation are also under continuous scrutiny. Evaluating novel root canal sealers, studies highlight their promising biocompatibility and antimicrobial properties, essential for long-term treatment success. Many new materials demonstrate superior characteristics compared to traditional options, though more in-vivo studies are needed to fully confirm their clinical benefits [4].

For immature permanent teeth with necrotic pulps, regenerative endodontic procedures offer a viable and often superior alternative to traditional apexification, proving highly effective in promoting root development and increasing tooth survival [5].

Diagnostic capabilities have seen significant advancements, with Cone-beam Computed Tomography (CBCT) playing a crucial role in diagnosing and managing endodontic complications. CBCT's superior 3D imaging significantly improves the detection of subtle issues like root fractures, missed canals, and periapical lesions, which are often invisible on conventional 2D radiographs [6].

Understanding the nature of infections is also paramount. A systematic review explored the diverse microbiological profile of primary endodontic infections, confirming their polymicrobial nature with a significant prevalence of anaerobic bacteria. This understanding is vital for selecting appropriate antimicrobial strategies [7].

Even with the best initial treatment, retreatment can be necessary. Studies assessing the efficacy of various techniques for removing root canal filling materials show that no single technique achieves complete removal, and residual material often remains despite the effectiveness of rotary and reciprocating systems combined with solvents [8].

Regarding instrumentation, Micro-Computed Tomography (micro-CT) studies evaluating the shaping ability of various Nickel-Titanium (NiTi) instruments in root canal preparation consistently show that modern NiTi systems significantly improve canal centering and reduce procedural errors compared to older techniques. However, achieving perfectly round canals in complex anatomies remains a challenge, underscoring the ongoing importance of operator skill [9].

Finally, for diagnostics of apical periodontitis in endodontically treated teeth, comparing traditional periapical radiography with CBCT reveals that CBCT consistently shows a significantly higher prevalence. This means 2D imaging often underestimates the extent of periapical disease, suggesting CBCT should be considered more frequently for accurate diagnosis and prognosis [10].

Description

Effective root canal treatment hinges on thorough disinfection and careful management of the root canal system. A persistent challenge in endodontics is the complete eradication of the smear layer, a crucial factor for successful treatment outcomes. While various irrigation techniques have been developed to improve smear layer removal, a comprehensive review indicates that none consistently achieve its complete elimination [1]. Specifically, techniques like passive ultrasonic irrigation and laser-activated irrigation show promise in enhancing cleanliness compared to conventional needle irrigation methods [1]. Beyond the smear layer, the disruption of tenacious bacterial biofilms presents another significant hurdle. Research suggests that adjunctive activation methods, when combined with conventional irrigants, notably enhance biofilm disruption. This underscores the necessity of employing advanced activation techniques beyond simple irrigation to achieve optimal disinfection, particularly within the complex anatomies of root canal systems [2]. The polymicrobial nature of primary endodontic infections, often dominated by anaerobic bacteria, further complicates disinfection strategies, highlighting the importance of a deep understanding of this microbial ecosystem for effective antimicrobial approaches [7].

The development of new materials and advanced therapeutic procedures continually refines endodontic practice. Novel root canal sealers, for instance, are being evaluated for their biocompatibility and antimicrobial properties, both of which are essential for the long-term success of treatments. Many of these newer materials demonstrate superior characteristics compared to traditional options, although more in-vivo studies are needed to fully validate their clinical benefits and ensure their integration into the biological environment of the root canal system [4]. Furthermore, regenerative endodontic procedures have emerged as a highly effective approach for immature permanent teeth presenting with necrotic pulps. These procedures are shown to promote root development and increase tooth survival, offering a viable and often superior alternative to traditional apexification methods. This advancement helps preserve the vitality and function of compromised young permanent teeth, a significant step forward in pediatric endodontics [5].

Accurate diagnosis is fundamental to successful treatment planning and case management. Cone-beam Computed Tomography (CBCT) has revolutionized diagnostics by providing superior three-dimensional imaging capabilities. This advanced imaging modality significantly improves the detection of subtle issues such as root fractures, missed canals, and periapical lesions, which frequently go undetected on conventional two-dimensional radiographs [6]. The implication here is that incorporating CBCT into diagnostic protocols can dramatically enhance treatment planning and prognosis, thereby reducing diagnostic errors in complex endodontic cases [6]. This diagnostic superiority is further underscored when assessing the prevalence of apical periodontitis in endodontically treated teeth. Studies comparing traditional periapical radiography with CBCT consistently reveal a significantly higher prevalence of apical periodontitis when CBCT is used, indicating that two-dimensional imaging often underestimates the true extent of periapical disease. Therefore, CBCT should be considered more frequently for precise diagnosis and prognosis in root canal treated teeth [10].

Procedural intricacies, such as root canal preparation and retreatment, also benefit from ongoing research and technological advancements. The shaping ability of various Nickel-Titanium (NiTi) instruments in root canal preparation has been thoroughly evaluated using Micro-Computed Tomography (micro-CT). These studies consistently demonstrate that modern NiTi systems improve canal centering and reduce procedural errors compared to older techniques. However, achieving perfectly round canals in complex anatomies remains a challenge, reinforcing the critical role of operator skill and careful technique [9]. In the context of retreatment, where previous root canal filling materials must be removed, it has been found that no single technique achieves complete removal. While rotary and reciprocating systems, often combined with solvent use, show good effectiveness, residual material frequently persists. This highlights the inherent difficulties in retreatment and emphasizes the need for meticulous execution to minimize any remaining remnants [8]. Lastly, even with advanced techniques, managing patient pain remains a concern. Despite the general efficacy of local anesthetics, a notable percentage of patients still report some degree of post-operative pain. This points to the need for individualized pain management strategies, possibly incorporating adjunct therapies, to ensure patient comfort throughout the entire treatment process [3].

Conclusion

Recent advancements in endodontics are focused on improving treatment efficacy, patient comfort, and diagnostic accuracy. Research shows that while modern irrigation techniques like passive ultrasonic and laser-activated irrigation enhance smear layer removal, complete elimination remains an ongoing challenge. Similarly, adjunctive activation methods are crucial for disrupting bacterial biofilms in complex root canal anatomies, moving beyond conventional irrigation alone. New root canal sealers demonstrate promising biocompatibility and antimicrobial properties, suggesting superior long-term success, though further in-vivo validation is necessary. Regenerative endodontic procedures are proving highly effective for immature teeth with necrotic pulps, offering a superior alternative to traditional treatments by promoting root development and survival. In diagnostics, Cone-beam Computed Tomography (CBCT) significantly surpasses 2D radiography in detecting endodontic complications like root fractures and periapical lesions, which are often underestimated by conventional imaging. Understanding the polymicrobial nature of primary endodontic infections is key for effective antimicrobial strategies. Challenges persist in retreatment, as no single technique guarantees complete removal of old filling materials, and in pain management, where individualized approaches are needed despite the general efficacy of local anesthetics. Finally, modern Nickel-Titanium instruments improve root canal shaping, but operator skill remains paramount for overcoming anatomical complexities.

References

  1. Xiaohui P, Lingrui W, Xiaoli M (2023) . BMC Oral Health 23:99.

    , ,

  2. Minjae K, Jin-Woo K, Young-Min K (2023) . J Endod 49:934-946.e1.

    , ,

  3. Amirhossein Y, Mehdi V, Fatemeh R (2023) . Clin Oral Investig 27:6327-6340.

    , ,

  4. Maryam G, Zahra Z, Mohammad AS (2023) . J Clin Exp Dent 15:e324-e332.

    , ,

  5. Bo W, Yuanyuan Z, Jie Z (2023) . Int Endod J 56:1335-1351.

    , ,

  6. Marília PG, Fernanda GVM, Isabella MIP (2023) . Clin Oral Investig 27:5127-5142.

    , ,

  7. Leticia L, Patrícia C, Ana MS (2023) . Int Endod J 56:1572-1589.

    , ,

  8. Xiaohui P, Lingrui W, Xiaoli M (2023) . Clin Oral Investig 27:5883-5899.

    , ,

  9. Chun-Feng W, Yu-Chun L, Chun-Liang L (2023) . J Endod 49:1478-1489.e1.

    , ,

  10. Wen-Bin Y, Hui-Juan X, Xin X (2023) . Clin Oral Investig 27:5937-5953.

    , ,

Citation: O芒聙聶Neil J (2025) Modern Endodontics: Advancements, Diagnostics, Regeneration, Challenges. J Oral Hyg Health 13: 521.

Copyright: 漏 2025 James O鈥橬eil This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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