Helicobacter Pylori Infection Induces Gastric Cancer and the Cancer/Testis Antigens Expression

Nobue Futawatari; Takashi Fukuyama; Rui Yamamura; Noritada Kobayash

doi:10.4172/2332-0877.1000345

ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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J Infect Dis Ther 2017, Vol 5(6): 345
DOI: 10.4172/2332-0877.1000345

Helicobacter Pylori Infection Induces Gastric Cancer and the Cancer/Testis Antigens Expression

Nobue Futawatari¹^#, Takashi Fukuyama²^*^#, Rui Yamamura² and Noritada Kobayash²: ¹Department of Surgery, school of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan; ²Division of Biomedical Research, Kitasato University Medical Center, Kitamoto, Saitama, Japan; ^#Contributed equally to this work

^*Corresponding Author : Takashi Fukuyama, Division of Biomedical Research, Kitasato University Medical Center, 6-100 Arai, Kitamoto, Saitama 364-8501, Japan, Tel: +81-48-593-1236, Fax: +81-48-593-1262, Email: fukuyam@insti.kitasato-u.ac.jp

Received Date: Dec 08, 2017 / Accepted Date: Dec 12, 2017 / Published Date: Dec 15, 2017

Abstract

Helicobacter pylori (HP) are known to induce gastritis, atrophy, intestinal metaplasia, dysplasia, and stomach malignancy. HP infection also induces cancer/testis antigens (CTAs) during or after gastric malignancy. This study aims to elucidate the relationship between HP and CTAs, especially melanoma antigen-A3 and Kitakyushu lung cancer antigen-1.

Keywords: Helicobacter pylori; Gastric cancer; Tumor antigen; Cancer/testis antigen; KK-LC-1; MAGE

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Citation: Futawatari N, Fukuyama T, Yamamura R, Kobayashi N (2017) Helicobacter Pylori Infection Induces Gastric Cancer and the Cancer/Testis Antigens Expression. J Infect Dis Ther 5: 345. Doi: 10.4172/2332-0877.1000345

Copyright: © 2017 Futuwatari N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Journal of Infectious Diseases & Therapy
天美传媒 Access