Case Report
First Case of Liver Abscess with Endogenous Endophthalmitis due toNon- K1/K2 Serotype Hypermucoviscous Klebsiella pneumoniae Clone ST268
Yuji Hirai1,3, Sayaka Asahata-Tago1, Yusuke Ainoda1, Takahiro Fujita3, Yutaka Uzawa1, Kaori Yamamoto2, Tomohiro Iida2 and Ken Kikuchi1*1Department of Infectious Diseases, Tokyo Women’s Medical University, Tokyo, Japan
2Department of Ophthalmology, Tokyo Women’s Medical University, Tokyo, Japan
3Faculty of Medicine, Department of General Medicine, Juntendo University, Tokyo, Japan
- *Corresponding Author:
- Ken Kikuchi, M.D. Ph.D.
Department of Infectious Diseases
Tokyo Women’s Medical University
8-1 Kawada-cho
Shinjuku-ku, Tokyo 162-8666, Japan
Tel: +81-3-3813-3111
Fax: +81-3-5684-7830
E-mail: kikuchi.ken@twmu.ac.jp
Received date: December 9, 2015; Accepted date: January 22, 2016; Published date: January 29, 2016
Citation: Hirai Y, Asahata-Tago S, Ainoda Y, Fujita T, Uzawa Y, et al. (2016) First Case of Liver Abscess with Endogenous Endophthalmitis due toNon-K1/K2 Serotype Hypermucoviscous Klebsiella pneumoniae Clone ST268. J Gastrointest Dig Syst 6:383. doi:10.4172/2161-069X.1000383
Copyright: © 2016 Hirai Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The hypermucoviscous (hv) Klebsiella pneumoniae (KP) can cause invasive liver abscess syndrome (ILAS) including endophthalmitis dominantly in eastern Asia. We report a 80-years old woman who diagnosed with invasive liver abscess syndrome due to K. pneumoniae (KP) non-K1/K2 hvKP multi-locus sequence type ST268 by DNA amplification methods isolated from blood culture. Soon she developed endogenous endopththalmitis and immediately right vitrectomy was performed. Although intravenous 2g of ceftriaxone (CTRX) was administrated, total enucleation of right eyeball had performed due to orbital cellulitis and necrosis of eye ball finally. To find complication (i.e. endophthalmitis) with caution and to select antimicrobial agents with sufficient penetration to CNS (i.e. ceftriaxone) is needed in a patient with severe hvKP infection. Usually ILAS is caused by K1/K2 hvKP. However, to our knowledge, this is a first report of ILAS with endophthalmitis and orbital cellulitis due to non-K1/K2 hvKP ST268.
