天美传媒

Abstract

This collection of systematic reviews and meta-analyses consistently demonstrates the significant efficacy and safety of Human Papillomavirus (HPV) vaccines, including Gardasil, Gardasil 9, and Cervarix. Studies highlight their effectiveness in preventing HPV infection, cervical intraepithelial neoplasia, anogenital warts, and high-grade cervical lesions across various populations and over the long term. Gardasil 9 offers broader protection, and gender-neutral programs show herd immunity benefits. The vaccines also provide cross-protection against non-vaccine HPV types, underscoring their crucial role in global cervical cancer prevention and public health.