天美传媒

ISSN: 2167-0846

Journal of Pain & Relief
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  • Commentary   
  • J Pain Relief ,
  • DOI: 10.4172/2167-0846.13.S3.002

Microvascular Dysfunction: An Overlooked Source of Local Pain Pathology

Terence J Coderre*
Department of Anesthesia, McGill University, Montreal, Canada
*Corresponding Author : Dr. Terence J Coderre, Department of Anesthesia, McGill University, Montreal, Canada, Email: terence.coderre@mcgill.ca

Received Date: Feb 01, 2024 / Published Date: Mar 04, 2024

Abstract

Microvascular dysfunction is an overlooked local pathology contributing to various chronic pains. Dysfunction in the microvasculature, including arterioles, capillaries, and arterioles contributes to inflammatory processes that impact local pain transmission both initiating pain and sensitizing nociceptors in pain syndromes such as Complex Regional Pain Syndrome (CRPS), fibromyalgia, and others.

Keywords: Endothelial cells, Microvascular injury, Oxidative stress, Antioxidants

Citation: Coderre TJ (2024) Microvascular Dysfunction: An Overlooked Source of Local Pain Pathology. J Pain Relief 天美传媒 S3: 002. Doi: 10.4172/2167-0846.13.S3.002

Copyright: © 2024 Coderre TJ. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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