Pharmacokinetic Variability in Special Populations: Implications for Dosing and Treatment Optimization in Clinical Pharmacology
Received Date: May 01, 2024 / Published Date: May 27, 2024
Abstract
Pharmacokinetic variability significantly impacts drug efficacy and safety, particularly in special populations such as the elderly, children, pregnant women, and individuals with comorbidities. This review explores the factors influencing pharmacokinetics within these groups, including changes in absorption, distribution, metabolism, and excretion. Understanding these variations is critical for optimizing dosing regimens and achieving therapeutic success. Individualized dosing strategies, pharmacogenetic testing, inclusive clinical trials, and continuous medical education are emphasized as essential tools for healthcare providers. By addressing the unique pharmacokinetic profiles of special populations, clinicians can enhance treatment outcomes and minimize adverse effects.
Citation: Adebawo M (2024) Pharmacokinetic Variability in Special Populations:Implications for Dosing and Treatment Optimization in Clinical Pharmacology. ClinPharmacol Biopharm, 13: 457.
Copyright: © 2024 Adebawo M. This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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